Cargando...

Characterization of the Effect of Hepatic Impairment on Upadacitinib Pharmacokinetics

Upadacitinib is a selective Janus kinase 1 inhibitor being developed for the treatment of several inflammatory autoimmune diseases, including rheumatoid arthritis. Upadacitinib is a nonsensitive substrate for metabolism by cytochrome P450 3A enzymes. This open‐label, single‐dose, multicenter study a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Pharmacol
Main Authors: Trueman, Sheryl, Mohamed, Mohamed‐Eslam F., Feng, Tian, Lacerda, Ana Paula, Marbury, Thomas, Othman, Ahmed A.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766976/
https://ncbi.nlm.nih.gov/pubmed/30973649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1414
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!