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Long‐Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor‐Specific Isoforms

Alternative splicing (AS) allows generation of cell type–specific mRNA transcripts and contributes to hallmarks of cancer. Genome‐wide analysis for AS in human hepatocellular carcinoma (HCC), however, is limited. We sought to obtain a comprehensive AS landscape in HCC and define tumor‐associated var...

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Bibliographic Details
Published in:Hepatology
Main Authors: Chen, Hui, Gao, Feng, He, Mian, Ding, Xiao Fan, Wong, Aikha M., Sze, Siu Ching, Yu, Allen C., Sun, Tingting, Chan, Anthony W‐H., Wang, Xin, Wong, Nathalie
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766942/
https://ncbi.nlm.nih.gov/pubmed/30637779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30500
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