Long‐Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor‐Specific Isoforms

Alternative splicing (AS) allows generation of cell type–specific mRNA transcripts and contributes to hallmarks of cancer. Genome‐wide analysis for AS in human hepatocellular carcinoma (HCC), however, is limited. We sought to obtain a comprehensive AS landscape in HCC and define tumor‐associated var...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Chen, Hui, Gao, Feng, He, Mian, Ding, Xiao Fan, Wong, Aikha M., Sze, Siu Ching, Yu, Allen C., Sun, Tingting, Chan, Anthony W‐H., Wang, Xin, Wong, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766942/
https://ncbi.nlm.nih.gov/pubmed/30637779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30500
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