Long‐Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor‐Specific Isoforms

Alternative splicing (AS) allows generation of cell type–specific mRNA transcripts and contributes to hallmarks of cancer. Genome‐wide analysis for AS in human hepatocellular carcinoma (HCC), however, is limited. We sought to obtain a comprehensive AS landscape in HCC and define tumor‐associated var...

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Publicado en:Hepatology
Autores principales: Chen, Hui, Gao, Feng, He, Mian, Ding, Xiao Fan, Wong, Aikha M., Sze, Siu Ching, Yu, Allen C., Sun, Tingting, Chan, Anthony W‐H., Wang, Xin, Wong, Nathalie
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766942/
https://ncbi.nlm.nih.gov/pubmed/30637779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30500
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