Evaluation of the Effects of a Monthly Buprenorphine Depot Subcutaneous Injection on QT Interval During Treatment for Opioid Use Disorder

Extensive 12‐lead electrocardiogram monitoring and drug concentrations were obtained during development of BUP‐XR, a monthly subcutaneous injection for the treatment of opioid use disorder (OUD). Matched QT and plasma drug concentrations (11,925) from 1,114 subjects were pooled from 5 studies in OUD...

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Dades bibliogràfiques
Publicat a:Clin Pharmacol Ther
Autors principals: Schmith, Virginia D., Curd, Laura, Lohmer, Lauren R. L., Laffont, Celine M., Andorn, Anne, Young, Malcolm A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766787/
https://ncbi.nlm.nih.gov/pubmed/30801681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1406
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