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Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial

IMPORTANCE: Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations. OBJECTIVE: To determine whether treatment involving novel weekly and monthly subcutaneous (SC) buprenorphine depot formulations is noninferior to a daily sublingual (SL) combination of bupr...

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Pubblicato in:JAMA Intern Med
Autori principali: Lofwall, Michelle R., Walsh, Sharon L., Nunes, Edward V., Bailey, Genie L., Sigmon, Stacey C., Kampman, Kyle M., Frost, Michael, Tiberg, Fredrik, Linden, Margareta, Sheldon, Behshad, Oosman, Sonia, Peterson, Stefan, Chen, Michael, Kim, Sonnie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145749/
https://ncbi.nlm.nih.gov/pubmed/29799968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2018.1052
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