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Population Pharmacokinetics of a Monthly Buprenorphine Depot Injection for the Treatment of Opioid Use Disorder: A Combined Analysis of Phase II and Phase III Trials

BACKGROUND: BUP-XR (a.k.a. RBP-6000 or SUBLOCADE™) is an extended-release subcutaneous buprenorphine formulation for the treatment of opioid use disorder. BUP-XR was designed to provide sustained buprenorphine exposure throughout the monthly dosing interval, at concentrations sufficient to control a...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Jones, Aksana K., Ngaimisi, Eliford, Gopalakrishnan, Mathangi, Young, Malcolm A., Laffont, Celine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016750/
https://ncbi.nlm.nih.gov/pubmed/33135125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00957-0
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