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Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells

A group of cytoprotective genes is regulated by heterodimers composed of the cap’n’collar (CNC) family member Nrf2 and one of the small Maf (sMaf) proteins (MafF, MafG, or MafK) through the antioxidant response element (ARE, also referred to as the CNC-sMaf binding element [CsMBE]). Many lines of ev...

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Publicat a:Mol Cell Biol
Autors principals: Katsuoka, Fumiki, Otsuki, Akihito, Takahashi, Mizue, Ito, Shin, Yamamoto, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766697/
https://ncbi.nlm.nih.gov/pubmed/31383749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00273-19
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