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Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells

A group of cytoprotective genes is regulated by heterodimers composed of the cap’n’collar (CNC) family member Nrf2 and one of the small Maf (sMaf) proteins (MafF, MafG, or MafK) through the antioxidant response element (ARE, also referred to as the CNC-sMaf binding element [CsMBE]). Many lines of ev...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Katsuoka, Fumiki, Otsuki, Akihito, Takahashi, Mizue, Ito, Shin, Yamamoto, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766697/
https://ncbi.nlm.nih.gov/pubmed/31383749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00273-19
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