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Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs

CB1 receptor (CB1R) antagonism improves the deleterious effects of a high-fat diet (HFD) by reducing body fat mass and adipocyte cell size. Previous studies demonstrated that the beneficial effects of the CB1R antagonist rimonabant (RIM) in white adipose tissue (WAT) are partially due to an increase...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Iyer, Malini S., Paszkiewicz, Rebecca L., Bergman, Richard N., Richey, Joyce M., Woolcott, Orison O., Asare-Bediako, Isaac, Wu, Qiang, Kim, Stella P., Stefanovski, Darko, Kolka, Cathryn M., Clegg, Deborah J., Kabir, Morvarid
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766608/
https://ncbi.nlm.nih.gov/pubmed/31237449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00539.2018
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