Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin

Although the β-cells secrete insulin, the liver, with its first-pass insulin extraction (FPE), regulates the amount of insulin allowed into circulation for action on target tissues. The metabolic clearance rate of insulin, of which FPE is the dominant component, is a major determinant of insulin sen...

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Bibliografiska uppgifter
I publikationen:Diabetes
Huvudupphovsmän: Asare-Bediako, Isaac, Paszkiewicz, Rebecca L., Kim, Stella P., Woolcott, Orison O., Kolka, Cathryn M., Burch, Miguel A., Kabir, Morvarid, Bergman, Richard N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2018
Ämnen:
Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054441/
https://ncbi.nlm.nih.gov/pubmed/29752425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1520
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