Assessment of hepatic insulin extraction from in vivo surrogate methods of insulin clearance measurement

Hyperinsulinemia, accompanied by reduced first-pass hepatic insulin extraction (FPE) and increased secretion, is a primary response to insulin resistance. Different in vivo methods are used to estimate the clearance of insulin, which is assumed to reflect FPE. We compared two methodologically differ...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Asare-Bediako, Isaac, Paszkiewicz, Rebecca L., Kim, Stella P., Woolcott, Orison O., Kolka, Cathryn M., Burch, Miguel, Kabir, Morvarid, Piccinini, Francesca, Bergman, Richard N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230713/
https://ncbi.nlm.nih.gov/pubmed/29509434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00344.2017
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