Translational effects and coding potential of an upstream open reading frame associated with DOPA Responsive Dystonia

Combination of bioinformatics, genome wide sequencing, transcriptomics and proteomics reveal a widespread impact of upstream open reading frames (uORFs) on translational regulation in eukaryotic species. In general, uORFs are repressive translational elements, initiated from a translation start site...

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Veröffentlicht in:Biochim Biophys Acta Mol Basis Dis
Hauptverfasser: Jones, Lataisia, Goode, Lacy, Davila, Eduardo, Brown, Amber, McCarthy, Deirdre M., Sharma, Nutan, Bhide, Pradeep G., Armata, Ioanna A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766408/
https://ncbi.nlm.nih.gov/pubmed/28366877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.03.024
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