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Selective Constraint on the Upstream Open Reading Frames That Overlap with Coding Sequences in Animals

Upstream open reading frames (uORFs) are translational regulatory elements located in 5′ untranslated regions. They can significantly repress the translation of the downstream coding sequences (CDS), and participate in the spatio-temporal regulations of protein translation. Notwithstanding this biol...

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Detalhes bibliográficos
Main Authors: Hsu, Ming-Kung, Chen, Feng-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486843/
https://ncbi.nlm.nih.gov/pubmed/23133632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048413
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