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Selective Constraint on the Upstream Open Reading Frames That Overlap with Coding Sequences in Animals

Upstream open reading frames (uORFs) are translational regulatory elements located in 5′ untranslated regions. They can significantly repress the translation of the downstream coding sequences (CDS), and participate in the spatio-temporal regulations of protein translation. Notwithstanding this biol...

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Autores principales: Hsu, Ming-Kung, Chen, Feng-Chi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486843/
https://ncbi.nlm.nih.gov/pubmed/23133632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048413
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