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Dopamine Receptor and Gα(olf) Expression in DYT1 Dystonia Mouse Models during Postnatal Development

BACKGROUND: DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG deletion (ΔGAG) in the DYT1 gene. Neuroimaging studies and studies using mouse models suggest that DYT1 dystonia is associated with dopamine imbalance. However, whether dopamine imbalance is key to DY...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Lin, McCarthy, Deirdre M., Sharma, Nutan, Bhide, Pradeep G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393110/
https://ncbi.nlm.nih.gov/pubmed/25860259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123104
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