High-definition spatial transcriptomics for in situ tissue profiling

Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking. Here, we developed High-Definition Spatial Transcriptomics (HDST), which captures RNA from histological tissue sections on a dense spatially barcoded bead array. Eac...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: Vickovic, Sanja, Eraslan, Gökcen, Salmén, Fredrik, Klughammer, Johanna, Stenbeck, Linnea, Schapiro, Denis, Äijö, Tarmo, Bonneau, Richard, Bergenstråhle, Ludvig, Navarro, José Fernandéz, Gould, Joshua, Griffin, Gabriel K., Borg, Åke, Ronaghi, Mostafa, Frisén, Jonas, Lundeberg, Joakim, Regev, Aviv, Ståhl, Patrik L
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765407/
https://ncbi.nlm.nih.gov/pubmed/31501547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0548-y
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