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Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity
Intra-tumor heterogeneity is one of the biggest challenges in cancer treatment today. Here we investigate tissue-wide gene expression heterogeneity throughout a multifocal prostate cancer using the spatial transcriptomics (ST) technology. Utilizing a novel approach for deconvolution, we analyze the...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010471/ https://ncbi.nlm.nih.gov/pubmed/29925878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04724-5 |
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