Phosphorylation of importin-α1 by CDK1–cyclin B1 controls mitotic spindle assembly

Importin-α serves as an adaptor linking importin-β to proteins carrying a nuclear localization sequence (NLS). During interphase, this interaction enables nuclear protein import, while in mitosis it regulates spindle assembly factors (SAFs) and controls microtubule nucleation, stabilization and spin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Guo, Li, Mohd, Khamsah Suryati, Ren, He, Xin, Guangwei, Jiang, Qing, Clarke, Paul R., Zhang, Chuanmao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765185/
https://ncbi.nlm.nih.gov/pubmed/31434716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232314
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