Phosphorylation of importin-α1 by CDK1–cyclin B1 controls mitotic spindle assembly

Importin-α serves as an adaptor linking importin-β to proteins carrying a nuclear localization sequence (NLS). During interphase, this interaction enables nuclear protein import, while in mitosis it regulates spindle assembly factors (SAFs) and controls microtubule nucleation, stabilization and spin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Guo, Li, Mohd, Khamsah Suryati, Ren, He, Xin, Guangwei, Jiang, Qing, Clarke, Paul R., Zhang, Chuanmao
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765185/
https://ncbi.nlm.nih.gov/pubmed/31434716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232314
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