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Phosphorylation of XIAP by CDK1–cyclin-B1 controls mitotic cell death

Regulation of cell death is crucial for the response of cancer cells to drug treatments that cause arrest in mitosis, and is likely to be important for protection against chromosome instability in normal cells. Prolonged mitotic arrest can result in cell death by activation of caspases and the induc...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Hou, Ying, Allan, Lindsey A., Clarke, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278668/
https://ncbi.nlm.nih.gov/pubmed/27927753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192310
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