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Phosphorylation of XIAP by CDK1–cyclin-B1 controls mitotic cell death

Regulation of cell death is crucial for the response of cancer cells to drug treatments that cause arrest in mitosis, and is likely to be important for protection against chromosome instability in normal cells. Prolonged mitotic arrest can result in cell death by activation of caspases and the induc...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Hou, Ying, Allan, Lindsey A., Clarke, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278668/
https://ncbi.nlm.nih.gov/pubmed/27927753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192310
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