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Phosphorylation of XIAP by CDK1–cyclin-B1 controls mitotic cell death

Regulation of cell death is crucial for the response of cancer cells to drug treatments that cause arrest in mitosis, and is likely to be important for protection against chromosome instability in normal cells. Prolonged mitotic arrest can result in cell death by activation of caspases and the induc...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Hou, Ying, Allan, Lindsey A., Clarke, Paul R.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278668/
https://ncbi.nlm.nih.gov/pubmed/27927753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192310
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