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Timed degradation of Mcl-1 controls mitotic cell death
Mitotic arrest can result in cell death through the process of apoptosis. We have shown by live-cell imaging that the ubiquitin-proteasome dependent proteolysis of the apoptotic regulator Mcl-1 under the control of the anaphase-promoting complex or cyclosome (APC/C) provides a timing mechanism that...
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| Gepubliceerd in: | Mol Cell Oncol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276845/ https://ncbi.nlm.nih.gov/pubmed/30525093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1516450 |
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