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A Metallaphotoredox Strategy for the Cross-Electrophile Coupling of α-Chloro Carbonyls with Aryl Halides

Here, we demonstrate that a metallaphotoredox-catalyzed cross-electrophile coupling mechanism provides a unified method for the α-arylation of diverse activated alkyl chlorides, including α-chloroketones, α-chloroesters, α-chloroamides, α-chlorocarboxylic acids, and benzylic chlorides. This strategy...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Chen, Tiffany Q., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764888/
https://ncbi.nlm.nih.gov/pubmed/31410960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201909072
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