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Dormant origin signaling during unperturbed replication
Mechanisms that limit origin firing are essential as the ~50,000 origins that replicate the human genome in unperturbed cells are chosen from an excess of ~500,000 licensed origins. Computational models of the spatiotemporal pattern of replication foci assume that origins fire stochastically with a...
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| Publicado en: | DNA Repair (Amst) |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764875/ https://ncbi.nlm.nih.gov/pubmed/31311769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102655 |
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