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Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering

Re‐epithelialization is a critical step in wound healing and results from the collective migration of keratinocytes. Previous work demonstrated that immobilized, but not soluble, epidermal growth factor (EGF) resulted in leader cell‐specific activation of phospholipase C gamma 1 (PLCγ1) in HaCaT ker...

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Detalhes bibliográficos
Publicado no:Bioeng Transl Med
Main Authors: Kim, Chloe S., Yang, Xinhai, Jacobsen, Sarah, Masters, Kristyn S., Kreeger, Pamela K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764804/
https://ncbi.nlm.nih.gov/pubmed/31572796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10138
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