Identification and Characterization of Functional Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein

Plasmodium vivax (Pv) invasion of reticulocytes relies on distinct receptor-ligand interactions between the parasite and host erythrocytes. Engagement of the highly polymorphic Pv Duffy-binding protein (DBPII) with the erythrocyte’s Duffy antigen receptor for chemokines (DARC) is essential. Some Pv-...

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Udgivet i:J Immunol
Main Authors: Carias, Lenore L., Dechavanne, Sebastien, Nicolete, Vanessa C., Sreng, Sokunthea, Suon, Seila, Amaratunga, Chanaki, Fairhurst, Rick M., Dechavanne, Celia, Barnes, Samantha, Witkowski, Benoit, Popovici, Jean, Roesch, Camille, Chen, Edwin, Ferreira, Marcelo U., Tolia, Niraj H., Adams, John H., King, Christopher L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764764/
https://ncbi.nlm.nih.gov/pubmed/30944159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801631
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