CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions

Microglia are specialized brain macrophages that play numerous roles in tissue homeostasis and response to injury. Colony stimulating factor 1 receptor (CSF1R) is a receptor tyrosine kinase required for the development, maintenance, and proliferation of microglia. Here we show that in adult mice per...

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Foilsithe in:Front Immunol
Main Authors: Easley-Neal, Courtney, Foreman, Oded, Sharma, Neeraj, Zarrin, Ali A., Weimer, Robby M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764286/
https://ncbi.nlm.nih.gov/pubmed/31616414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02199
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