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Genome mining- and synthetic biology-enabled production of hypermodified peptides
The polytheonamides are among the most complex and biosynthetically distinctive natural products known to date. These potent peptide cytotoxins are derived from a ribosomal precursor processed by 49 mostly non-canonical posttranslational modifications. Since the producer is a "microbial dark ma...
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| Publicado no: | Nat Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6763334/ https://ncbi.nlm.nih.gov/pubmed/31501509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0323-9 |
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