STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade

The stimulator of IFN genes (STING) signaling pathway is a critical link between innate and adaptive immunity and induces antitumor immune responses. STING is expressed in vasculatures, but its role in tumor angiogenesis has not been elucidated. Here, we investigated STING-induced tumor vascular rem...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Yang, Hannah, Lee, Won Suk, Kong, So Jung, Kim, Chang Gon, Kim, Joo Hoon, Chang, Sei Kyung, Kim, Sewha, Kim, Gwangil, Chon, Hong Jae, Kim, Chan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763266/
https://ncbi.nlm.nih.gov/pubmed/31343989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125413
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