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Combination of anti-angiogenic therapy and immune checkpoint blockade normalizes vascular-immune crosstalk to potentiate cancer immunity

Cancer immunotherapy with immune checkpoint inhibitors (ICIs) has revolutionized the treatment of advanced cancers. However, the tumor microenvironment (TME) functions as a formidable barrier that severely impairs the efficacy of ICIs. While the crosstalk between tumor vessels and immune cells deter...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Won Suk, Yang, Hannah, Chon, Hong Jae, Kim, Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080646/
https://ncbi.nlm.nih.gov/pubmed/32913278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00500-y
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