A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity

While a high frequency of Th1 cells in tumors is associated with improved cancer prognosis, this benefit has been attributed mainly to support of cytotoxic activity of CD8(+) T cells. By attempting to potentiate antibody-driven immunity, we found a remarkable synergy between CD4(+) T cells and tumor...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rasoulouniriana, Diana, Santana-Magal, Nadine, Gutwillig, Amit, Farhat-Younis, Leen, Wine, Yariv, Saperia, Corey, Tal, Lior, Gutman, Haim, Tsivian, Alexander, Brenner, Ronen, Bandora, Eiman Abu, Reticker-Flynn, Nathan E., Rider, Peleg, Carmi, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763258/
https://ncbi.nlm.nih.gov/pubmed/31449054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127590
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