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Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues

The role of B cells in the tumor microenvironment (TME) has largely been under investigated, and data regarding the antibody repertoire encoded by B cells in the TME and the adjacent lymphoid organs are scarce. Here, we utilized B cell receptor high-throughput sequencing (BCR-Seq) to profile the ant...

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Publicado en:Front Immunol
Autores principales: Aizik, Ligal, Dror, Yael, Taussig, David, Barzel, Adi, Carmi, Yaron, Wine, Yariv
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327180/
https://ncbi.nlm.nih.gov/pubmed/34349765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.705381
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