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Type I IFN protects cancer cells from CD8(+) T cell–mediated cytotoxicity after radiation
Treatment of tumors with ionizing radiation stimulates an antitumor immune response partly dependent on induction of IFNs. These IFNs directly enhance dendritic cell and CD8(+) T cell activity. Here we show that resistance to an effective antitumor immune response is also a result of IFN signaling i...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6763250/ https://ncbi.nlm.nih.gov/pubmed/31483286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127458 |
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