synaptotagmin Mutants Reveal Essential Functions for the C2B Domain in Ca(2+)-Triggered Fusion and Recycling of Synaptic Vesicles In Vivo

Synaptotagmin has been proposed to function as a Ca(2+) sensor that regulates synaptic vesicle exocytosis, whereas the solubleN-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex is thought to form the core of a conserved membrane fusion machine. Little is known concerning t...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Littleton, J. Troy, Bai, Jihong, Vyas, Bimal, Desai, Radhika, Baltus, Andrew E., Garment, Martin B., Carlson, Stanley D., Ganetzky, Barry, Chapman, Edwin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762938/
https://ncbi.nlm.nih.gov/pubmed/11222632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01421.2001
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