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Activation of Expressed KCNQ Potassium Currents and Native Neuronal M-Type Potassium Currents by the Anti-Convulsant Drug Retigabine

Retigabine [D-23129;N-(2-amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester] is a novel anticonvulsant compound that is now in clinical phase II development. It has previously been shown to enhance currents generated by KCNQ2/3 K(+) channels when expressed in Chinese hamster ovary (CHO)...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Tatulian, L., Delmas, P., Abogadie, F. C., Brown, D. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762632/
https://ncbi.nlm.nih.gov/pubmed/11466425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-15-05535.2001
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