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Chronic Exposure to Nicotine Upregulates the Human α4β2 Nicotinic Acetylcholine Receptor Function

Widely expressed in the brain, the α4β2 nicotinic acetylcholine receptor (nAChR) is proposed to play a major role in the mechanisms that lead to and maintain nicotine addiction. Using the patch-clamp technique and pharmacological protocols, we examined the consequences of long-term exposure to 0.1–1...

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Publicat a:J Neurosci
Autors principals: Buisson, Bruno, Bertrand, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762627/
https://ncbi.nlm.nih.gov/pubmed/11245666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-06-01819.2001
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