Functional Characterization of AT-1001, an α3β4 Nicotinic Acetylcholine Receptor Ligand, at Human α3β4 and α4β2 nAChR

INTRODUCTION: Genome-wide association studies linking the α3, β4, and α5 nicotinic acetylcholine receptor (nAChR) subunits to nicotine dependence suggest that α3β4* nAChR may be targets for smoking cessation pharmacotherapies. We previously reported that AT-1001, a selective α3β4* nAChR ligand binds...

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Bibliografiska uppgifter
I publikationen:Nicotine Tob Res
Huvudupphovsmän: Zaveri, Nurulain T., Bertrand, Sonia, Yasuda, Dennis, Bertrand, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Brief Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837995/
https://ncbi.nlm.nih.gov/pubmed/25180076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntu170
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