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AT–1001: a high-affinity α3β4 nAChR ligand with novel nicotine-suppressive pharmacology
BACKGROUND AND PURPOSE: The α3β4 subtype of nicotinic acetylcholine receptors (nAChRs) has been implicated in mediating nicotine reinforcement processes. AT-1001 has been recently described as a high-affinity and selective α3β4 nAChR antagonist that blocks nicotine self-administration in rats. The a...
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| Udgivet i: | Br J Pharmacol |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376460/ https://ncbi.nlm.nih.gov/pubmed/25440006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13034 |
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