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Chronic Nicotine Exposure Upregulates Nicotinic Receptors by a Novel Mechanism

Nicotine addiction is initiated by its binding to high-affinity nicotinic receptors in brain composed primarily of α4 and β2 subunits. For nicotinic receptors expressed in vivo or heterologously, nicotine exposure over hours to days increases or “upregulates” high-affinity nicotine binding to recept...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vallejo, Yolanda F., Buisson, Bruno, Bertrand, Daniel, Green, William N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246082/
https://ncbi.nlm.nih.gov/pubmed/15944384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5240-04.2005
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