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Chronic Nicotine Exposure Upregulates Nicotinic Receptors by a Novel Mechanism
Nicotine addiction is initiated by its binding to high-affinity nicotinic receptors in brain composed primarily of α4 and β2 subunits. For nicotinic receptors expressed in vivo or heterologously, nicotine exposure over hours to days increases or “upregulates” high-affinity nicotine binding to recept...
Tallennettuna:
| Päätekijät: | , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Society for Neuroscience
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246082/ https://ncbi.nlm.nih.gov/pubmed/15944384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5240-04.2005 |
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