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Chronic Nicotine Exposure Upregulates Nicotinic Receptors by a Novel Mechanism
Nicotine addiction is initiated by its binding to high-affinity nicotinic receptors in brain composed primarily of α4 and β2 subunits. For nicotinic receptors expressed in vivo or heterologously, nicotine exposure over hours to days increases or “upregulates” high-affinity nicotine binding to recept...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2005
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246082/ https://ncbi.nlm.nih.gov/pubmed/15944384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5240-04.2005 |
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