Caspase-Activated DNase/DNA Fragmentation Factor 40 Mediates Apoptotic DNA Fragmentation in Transient Cerebral Ischemia and in Neuronal Cultures

Nuclear changes, including internucleosomal DNA fragmentation, are characteristic features of neuronal apoptosis resulting from transient cerebral ischemia and related brain insults for which the molecular mechanism has not been elucidated. Recent studies suggest that a caspase-3-mediated mechanism...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cao, Guodong, Pei, Wei, Lan, Jing, Stetler, R. Anne, Luo, Yumin, Nagayama, Tetsuya, Graham, Steven H., Yin, Xiao-Ming, Simon, Roger P., Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762351/
https://ncbi.nlm.nih.gov/pubmed/11425895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-13-04678.2001
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