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Structural Determinants of Fast Desensitization and Desensitization–Deactivation Coupling in GABA(A)Receptors

Fast IPSCs in the brain are predominantly caused by presynaptic release of GABA that activates GABA(A)receptor (GABA(A)R) channels. The IPSCs are shaped by the gating and desensitization properties of postsynaptic GABA(A)Rs. Specifically, fast desensitization has been suggested to decrease IPSC ampl...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Bianchi, Matt T., Haas, Kevin F., Macdonald, Robert L.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762234/
https://ncbi.nlm.nih.gov/pubmed/11160383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-04-01127.2001
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