The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

Efficient adaptation to iron starvation is an essential virulence determinant of the most common human mold pathogen, Aspergillus fumigatus. Here, we demonstrate that the cytosolic monothiol glutaredoxin GrxD plays an essential role in iron sensing in this fungus. Our studies revealed that (i) GrxD...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Misslinger, Matthias, Scheven, Mareike Thea, Hortschansky, Peter, López-Berges, Manuel Sánchez, Heiss, Katharina, Beckmann, Nicola, Heigl, Thomas, Hermann, Martin, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A., Haas, Hubertus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762210/
https://ncbi.nlm.nih.gov/pubmed/31525190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008379
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