The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

Efficient adaptation to iron starvation is an essential virulence determinant of the most common human mold pathogen, Aspergillus fumigatus. Here, we demonstrate that the cytosolic monothiol glutaredoxin GrxD plays an essential role in iron sensing in this fungus. Our studies revealed that (i) GrxD...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Misslinger, Matthias, Scheven, Mareike Thea, Hortschansky, Peter, López-Berges, Manuel Sánchez, Heiss, Katharina, Beckmann, Nicola, Heigl, Thomas, Hermann, Martin, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A., Haas, Hubertus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762210/
https://ncbi.nlm.nih.gov/pubmed/31525190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008379
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