The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

Efficient adaptation to iron starvation is an essential virulence determinant of the most common human mold pathogen, Aspergillus fumigatus. Here, we demonstrate that the cytosolic monothiol glutaredoxin GrxD plays an essential role in iron sensing in this fungus. Our studies revealed that (i) GrxD...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Misslinger, Matthias, Scheven, Mareike Thea, Hortschansky, Peter, López-Berges, Manuel Sánchez, Heiss, Katharina, Beckmann, Nicola, Heigl, Thomas, Hermann, Martin, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A., Haas, Hubertus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762210/
https://ncbi.nlm.nih.gov/pubmed/31525190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008379
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