The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans

The acquisition of iron and the maintenance of iron homeostasis are important aspects of virulence for the pathogenic fungus Cryptococcus neoformans. In this study, we characterized the role of the monothiol glutaredoxin Grx4 in iron homeostasis and virulence in C. neoformans. Monothiol glutaredoxin...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Attarian, Rodgoun, Hu, Guanggan, Sánchez-León, Eddy, Caza, Mélissa, Croll, Daniel, Do, Eunsoo, Bach, Horacio, Missall, Tricia, Lodge, Jennifer, Jung, Won Hee, Kronstad, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282196/
https://ncbi.nlm.nih.gov/pubmed/30514787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02377-18
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