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Grx4 Monothiol Glutaredoxin Is Required for Iron Limitation-Dependent Inhibition of Fep1

The expression of iron transport genes in Schizosaccharomyces pombe is controlled by the Fep1 transcription factor. When iron levels exceed those needed by the cells, Fep1 represses iron transport genes. In contrast, Fep1 is unable to bind chromatin under low-iron conditions, and that results in act...

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Auteurs principaux: Jbel, Mehdi, Mercier, Alexandre, Labbé, Simon
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127657/
https://ncbi.nlm.nih.gov/pubmed/21421748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00015-11
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