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Heat shock-induced chaperoning by Hsp70 is enabled in-cell

Recent work has shown that weak protein-protein interactions are susceptible to the cellular milieu. One case in point is the binding of heat shock proteins (Hsps) to substrate proteins in cells under stress. Upregulation of the Hsp70 chaperone machinery at elevated temperature was discovered in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Guin, Drishti, Gelman, Hannah, Wang, Yuhan, Gruebele, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762143/
https://ncbi.nlm.nih.gov/pubmed/31557226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222990
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