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Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species

The Dot/Icm type IVB secretion system of Legionella pneumophila is essential for its pathogenesis by delivering >300 effector proteins into the host cell. However, their precise secretion mechanism and which components interact with the host cell is only partly understood. Here, we undertook evol...

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Détails bibliographiques
Publié dans:Genome Biol Evol
Auteurs principaux: Gomez-Valero, Laura, Chiner-Oms, Alvaro, Comas, Iñaki, Buchrieser, Carmen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761968/
https://ncbi.nlm.nih.gov/pubmed/31504472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz186
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