Dot/Icm-Dependent Restriction of Legionella pneumophila within Neutrophils

The Dot/Icm type IV secretion system (T4SS) of Legionella pneumophila is essential for lysosomal evasion and permissiveness of macrophages for intracellular proliferation of the pathogen. In contrast, we show that polymorphonuclear cells (PMNs) respond to a functional Dot/Icm system through rapid re...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Price, Christopher T. D., Hanford, Hannah E., Vashishta, Aruna, Ozanic, Mateja, Santic, Marina, Uriarte, Silvia, Kwaik, Yousef Abu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262857/
https://ncbi.nlm.nih.gov/pubmed/34076467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01008-21
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