Dot/Icm-Dependent Restriction of Legionella pneumophila within Neutrophils

The Dot/Icm type IV secretion system (T4SS) of Legionella pneumophila is essential for lysosomal evasion and permissiveness of macrophages for intracellular proliferation of the pathogen. In contrast, we show that polymorphonuclear cells (PMNs) respond to a functional Dot/Icm system through rapid re...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Price, Christopher T. D., Hanford, Hannah E., Vashishta, Aruna, Ozanic, Mateja, Santic, Marina, Uriarte, Silvia, Kwaik, Yousef Abu
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262857/
https://ncbi.nlm.nih.gov/pubmed/34076467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01008-21
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