Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy

BACKGROUND: In mammals, muscle contraction is controlled by a family of 10 sarcomeric myosin motors. The expression of one of its members, MYH7b, is regulated by alternative splicing, and while the protein is restricted to specialized muscles such as extraocular muscles or muscle spindles, RNA that...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Peter, Angela K., Rossi, Alberto C., Buvoli, Massimo, Ozeroff, Christopher D., Crocini, Claudia, Perry, Amy R., Buvoli, Ada E., Lee, Lindsey A., Leinwand, Leslie A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761648/
https://ncbi.nlm.nih.gov/pubmed/31364453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013318
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