Inhibition of Senescence‐Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction

BACKGROUND: Myocardial infarction results in a large‐scale cardiomyocyte loss and heart failure due to subsequent pathological remodeling. Whereas zebrafish and neonatal mice have evident cardiomyocyte expansion following injury, adult mammalian cardiomyocytes are principally nonproliferative. Despi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Heart Assoc
Päätekijät: Alam, Perwez, Haile, Bereket, Arif, Mohammed, Pandey, Raghav, Rokvic, Miso, Nieman, Michelle, Maliken, Bryan D., Paul, Arghya, Wang, Yi‐Gang, Sadayappan, Sakthivel, Ahmed, Rafeeq P. H., Kanisicak, Onur
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761626/
https://ncbi.nlm.nih.gov/pubmed/31315484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012089
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