Multiplex Epigenome Editing of Dorsal Root Ganglion Neuron Receptors Abolishes Redundant Interleukin 6, Tumor Necrosis Factor Alpha, and Interleukin 1β Signaling by the Degenerative Intervertebral Disc

Back pain is the leading cause of disability worldwide and contributes to significant socioeconomic impacts. It has been hypothesized that the degenerative intervertebral disc (IVD) contributes to back pain by sensitizing nociceptive neurons innervating the IVD to stimuli that would not be painful t...

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Vydáno v:Hum Gene Ther
Hlavní autoři: Stover, Joshua D., Farhang, Niloofar, Lawrence, Brandon, Bowles, Robby D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761584/
https://ncbi.nlm.nih.gov/pubmed/31056946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.032
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