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Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment

Chagas’ disease, which is caused by the Trypanosoma cruzi parasite, has become a global health problem that is currently treated with poorly tolerated drugs that require prolonged dosing. Therefore, there is a clinical need for new therapeutic agents that can mitigate these issues. The phosphomannom...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Zmuda, Filip, Shepherd, Sharon M., Ferguson, Michael A. J., Gray, David W., Torrie, Leah S., De Rycker, Manu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761512/
https://ncbi.nlm.nih.gov/pubmed/31405854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01082-19
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