Patient-to-Patient Transmission of Klebsiella pneumoniae Carbapenemase Variants with Reduced Ceftazidime-Avibactam Susceptibility

We report patient-to-patient transmission of Enterobacter hormaechei isolates with reduced susceptibility to ceftazidime-avibactam due to production of KPC-40, a variant of KPC-3 with a two-amino-acid insertion in the Ω-loop region (L167_E168dup). The index patient had received a prolonged course of...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Munoz-Price, L. Silvia, Reeme, Allison E., Buchan, Blake W., Mettus, Roberta T., Mustapha, Mustapha M., Van Tyne, Daria, Shields, Ryan K., Doi, Yohei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761506/
https://ncbi.nlm.nih.gov/pubmed/31332070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00955-19
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